JN Beauty Solutions™
BRILLIANCE ESSENCE CREAM SERUM
WITH TRANEXAMIC ACID & ALPHA ARBUTIN
Tranexamic Acid is a water-soluble synthetic derivative of the amino acid Lysine. In medical specialties, this is a substance that helps blood clot by inhibiting the activation of plasminogen to plasmin, a molecule that plays an important role in breaking down fibrin, the basic component of blood clots during the hemostasis process.
Tranexamic Acid was discovered and published by scientists in 1962. It is listed among the most effective and safe drugs today. In particular, Tranexamic Acid is considered an essential medicine on the World Health Organization (WHO) list.
In 1979, doctors observed that patients treated with Tranexamic Acid to stop bleeding showed marked improvement in skin color. Since then, Tranexamic Acid has been widely used in cosmetics to nourish the skin and treat melasma in various forms, such as Tranexamic Acid or M-Tranexamic Acid.
Basically, Tranexamic Acid can help solve three of the most stubborn skin care problems: pigmentation, melasma, and age spots:
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Treatment of melasma, tanning, freckles, and sunburn; melasma often occurs due to hormonal disturbances during pregnancy.
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Visibly supports the fading of post-acne scars and reduces the formation of acne scars.
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Prevents the accumulation of melanin pigment, brightens the skin.
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Anti-allergic, reduces skin irritation, and minimizes redness.
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Anti-inflammatory properties.
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Reduces capillary proliferation during pigmentation treatment.
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Soothes the skin, limits irritation, and supports melasma treatment.
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Restores pigmentation and skin layers damaged by ultraviolet rays.
In a trial conducted with 28 patients with melasma and 5 patients with freckles, treatment with Tranexamic Acid for 5–18 weeks helped 80% of women with melasma and 75% of women with freckles see visible improvement, with brighter and more even skin tone.
When compared with other skincare ingredients such as Azelaic Acid, L-Ascorbic Acid, and Arbutin, Tranexamic Acid shows superior multifunctional effectiveness, including anti-inflammatory, dark spot reduction, anti-irritation, and greater stability when exposed to light and high temperatures.
The effectiveness of Tranexamic Acid in treating melasma is comparable to that of Hydroquinone (a skin-lightening substance), but without Hydroquinone’s side effects. Nearly 96% of study participants using Tranexamic Acid noticed improvement in melasma and discoloration after 12 weeks of daily use when combined with sun protection.
SIDE EFFECTS OF TRANEXAMIC ACID:
Although Tranexamic Acid is gentle for most skin types, people with super sensitive skin or eczema should perform a patch test before using it.
Tranexamic Acid eliminates melasma by blocking the interaction between keratinocytes (skin cells) and melanocytes (melanin-producing cells), thereby inhibiting melanin synthesis — the primary cause of dark spots and skin discoloration.
Additionally, it helps reduce the number of weak skin cells, reducing inflammation, itchiness, and irritation. Tranexamic Acid also slows melanin production by competitively inhibiting tyrosinase due to its structural similarity to tyrosine.
In theory, Tranexamic Acid can be incorporated into almost anyone’s skincare routine. Unlike other acid ingredients, Tranexamic Acid does not provide exfoliation or collagen-stimulating benefits. Instead, it is reserved for those seeking to improve hyperpigmentation, particularly in regions like Asia and Vietnam, where melasma and pigment disorders are common.
Kilgore, a leading dermatologist, says, “If you have a lot of dark spots, apply a product with Tranexamic Acid all over your face during the day after cleansing, toning, and using an AHA exfoliant or BHA. Follow with serum or any other treatment product, and finish with sun protection. You can use it topically during the day, apply it to darkened areas, and finish with sun protection. You can follow the same routine at night, followed by other treatments and then moisturizer.”
Kilgore also emphasizes that consistent use is crucial to successfully fade hyperpigmentation. “Most people will notice results with regular use in 8–12 weeks. Research has shown that Tranexamic Acid is safe when applied to the skin daily for several months,” she explains.
Topical concentrations of 2–5% typically show results after 2–3 months of once or twice-daily use. However, it’s important to note that Tranexamic Acid is a water-soluble ingredient, which means it should be used alongside oil-soluble products, like oil-based moisturizers, especially for those with dry skin. The addition of emollients helps prevent skin dryness caused by acids, resulting in a healthy and balanced skin barrier.
“Tranexamic Acid shows promising results when used to reduce unwanted hyperpigmentation,” says Dr. Deborah Lee.
Hyperpigmentation is a common skincare concern, yet until recently, the topical use of Tranexamic Acid was not widely recognized as a potential treatment. Tranexamic Acid has gained popularity through social media, influencers, and the endorsement of consultant dermatologists. It has been described as a “hero ingredient” due to its potent skin benefits. Dr. David Lim even calls it “one of the biggest breakthroughs in the treatment of pigmentation, especially melasma.”
“Tranexamic Acid, a derivative of the amino acid lysine, is currently one of the best pigment-correcting actives for improving blemishes,” says Joanne Healy, Product Development Manager at Advanced Skin Technology.
It targets dark spots and uneven pigmentation while also supporting sunscreen’s function to soothe, condition, and protect the skin from environmental damage. Tranexamic Acid’s unique action fades dark spots and significantly calms redness and hyperpigmentation.
Beauty Magazine has also noted the anti-inflammatory properties of Tranexamic Acid. Unlike exfoliating acids like glycolic acid and salicylic acid, Tranexamic Acid does not exfoliate the skin. Instead, it acts as a potent anti-inflammatory, disrupting the overproduction of melanin caused by inflammation. While melanin is essential for skin protection, its overproduction leads to dark patches, spots, and dullness.
It can be said that Tranexamic Acid is a versatile ingredient that helps fade pigmentation, dark spots, acne scars, and brown spots caused by sun exposure.
After only 6–8 weeks of continuous use, you will see a significant improvement in skin clarity. When combined with professional melasma treatments from JN Beauty Solutions, such as Diamond Bright Pigment Night Gel or Diamond Bright Night Cream, results can be doubled within just 2–4 weeks.
Currently, laboratories often combine Tranexamic Acid with other ingredients to enhance its effectiveness in treating dark spots, pigmentation, and skin brightening. Ingredients such as Vitamin C and its derivatives (L-cysteine, Ascorbic Acid, L-Ascorbic Acid) support deeper penetration and improved absorption, especially in darker skin tones. However, when combined with Alpha Arbutin — one of the safest and most effective skin-lightening agents — the results become even more pronounced.
LET’S LEARN A LITTLE ABOUT ALPHA ARBUTIN:
Arbutin is a familiar skin-whitening ingredient in most high-end cosmetic lines. Chemically, Arbutin is a form of Hydroquinone (a skin-lightening agent), but its molecule contains glucose. This glucose component is what differentiates how Hydroquinone and Arbutin work, and Arbutin has been approved by the FDA. Unlike Hydroquinone, which destroys melanocytes, Arbutin inhibits the enzyme responsible for melanin production in cells. Because of this different mechanism, Arbutin is a gentler skin-lightening agent with fewer unwanted side effects, though its results may develop more gradually.
Arbutin exists in two forms: alpha and beta. The alpha form is more stable and has a stronger inhibitory effect on melanin production. Naturally, Alpha-Arbutin is extracted from bearberry plants, which grow in various regions across North and South America. It is also found in wheat germ, pear skin, and blueberry leaves. However, extracting Arbutin from nature is challenging, so many laboratories synthesize it. Nonetheless, reputable and high-quality brands invest in natural Alpha-Arbutin extracts, as Alpha-Arbutin is considered 10 times more effective than other forms.
ALPHA ARBUTIN’S MECHANISM OF ACTION:
Alpha Arbutin works through a controlled-release mechanism that inhibits the oxidation of L-tyrosine (a process catalyzed by tyrosinase) and counters tyrosinase binding activity. Because of its glucose molecule, Arbutin inhibits the enzyme responsible for melanin production without destroying melanocytes, allowing for a gentler yet effective whitening effect without the side effects associated with Hydroquinone.
Additionally, because Alpha Arbutin releases its active component slowly, it causes less irritation compared to direct-use Hydroquinone, offering safer, steadier results that don’t compromise skin health.
Research into Arbutin’s tyrosinase-inhibiting capacity dates back to the 1990s. There’s promising evidence that Alpha-Arbutin and Deoxyarbutin are effective skin lighteners, though much of this research comes from in vitro and animal studies.
BENEFITS OF ARBUTIN FOR SKIN:
Arbutin is a true skincare elixir found in many beauty products for a reason. Its benefits include:
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Reducing pigmentation and tanning caused by UV exposure by inhibiting melanocyte activity.
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Evening out skin tone and fading long-standing brown spots.
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Offering antioxidant protection, preventing premature aging, and rejuvenating the skin.
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Being the top choice for melasma and freckle-prone skin by depleting melanin accumulation in skin layers.
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Clinical studies show visible improvements when using Arbutin at concentrations of 1% or higher, especially when combined with agents like Kojic Acid. Products with Alpha Arbutin yield noticeable results after 2–3 months of consistent use.
Alpha Arbutin’s key appeal lies in its safety. No research has conclusively shown that long-term, high-dosage use harms the skin. Concentrations used in cosmetic products are well-regulated to maximize benefits safely. For those seeking a safe, effective, and side-effect-free skin-brightening ingredient, Alpha Arbutin remains a top choice.
When we combined Alpha Arbutin and Tranexamic Acid into the JN Beauty Solutions™ Brilliance Essence Serum, our goal was to provide consumers with a safer and more sustainable solution to melasma and pigmentation problems. Beyond brightening, inhibiting melanin production, and reducing inflammation, this serum aims to restore a clean, healthy skin foundation.
The launch of JN Beauty Solutions™ Brilliance Essence in 2022 marks not only a new product milestone but also celebrates two years of our brand’s commitment to delivering professional-grade, high-quality skincare solutions.
The product underwent over 15 months of practical testing before its official launch, is 100% made in the USA, and is committed to offering consumers unparalleled safety and effectiveness.
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JN BEAUTY SOLUTIONS™
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